… neurotransmitters, neuromodulatory regulators, or from a trigger … , ketamine administration
also increases the AMPA to NMDA … -95, the target of GSK-3 that would promote AMPA-GluA1 …

… activation of AMPA receptors, which trigger mammalian target of … suggests that ketamine
act through regulation of brain-… ketamine enantiomers and metabolites to NMDA-R or AMPA-…

… GSK-3: a key regulatory target for ketamine's rapid antidepressant effects mediated by
enhanced AMPA to NMDA throughput. Bipolar Disord 2016; 18: 702–705, doi: 10.1111/bdi.12452…

… signaling can inhabit GSK-3 activity; GSK-3 can inhibit mTOR … In conclusion, since
ketamine-induced side effects must be … nonselective NMDA receptor antagonist that activates …

… The goal of the article is to contribute to better understanding and treatment of TRD, which
… kinase 3 (GSK-3) and AMPA receptors in the antidepressant effects of ketamine are also …

… that antidepressant effects of ketamine, a NMDA receptor … pathways including inhibition of
GSK-3 activity by PI3K-Akt … of the NMDA receptors and is necessary for membrane targeting, …

… target of rapamycin (mTOR), extracellular signal-regulated kinase (… Hypothetically, these
pyramidal neurons rely on AMPA … , phosphorylation of GSK-3 might be caused by the ketamine-…

… targeting BDNF and Trk-B with ketamine treatment147, 148. … linked to improvement of AMPA
throughput, and followed by … GSK-3 inhibitor lithium enhances the antidepressant effects …

… The aim of this study was to summarize and highlight the … non-NMDA-mediated affects
of ketamine are summarized in … , AMPA was found to be an essential element in mediating …

… the structure of GSK-3, the regulation of GSK-3 activity, and … of NMDA receptor-mediated
signaling by ketamine evoked … apparent that GSK-3 is a promising therapeutic target due to its …